Zirconium (IV) chloride catalyzed new and efficient protocol for the selective cleavage of p-methoxybenzyl ethers

…, C GOVARDHAN REDDY, PR KRISHNA

文献索引：Madhava Sharma, Gangavaram V.; Reddy, Ch. Govardhan; Krishna, Palakodety Radha Journal of Organic Chemistry, 2003 , vol. 68, # 11 p. 4574 - 4575

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被引用次数: 3

摘要

Résumé/Abstract A highly selective and efficient method for the unmasking ofp- methoxybenzyl (PMB) ethers and esters has been developed by use of 20 mol% of zirconium (IV) chloride as Lewis acid in acetonitrile. The present method is very fast, and the conditions are tolerable to a variety of acid/base-sensitive protecting groups and substrates such as carbohydrates, terpenes, and amino acids. The products are obtained in good to ...