Synthesis of Aryl Urea Derivatives from Aryl Amines and Aryl Isocyanates

V Usharani, B Rao, MP Reddy…

文献索引：Usharani; Bhujanga Rao; Reddy; Dubey Asian Journal of Chemistry, 2011 , vol. 23, # 4 p. 1802 - 1806

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被引用次数: 1

摘要

Abstract The present study describes the synthesis of novel diaryl urea derivatives derived from aryl amine and aryl isocyanates. The synthesized compounds are analogs of sorafenib [4-[4-[[[4-chloro-3-(trifluoromethyl) phenyl] amino] carbonyl] amino] phenoxy]-N- methylpyridine-2-carboxamide] having potential antiproliferative activity.