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Synthesis of Pyridines and Pyrazines Using an Intramolecular Hydroamination??Based Reaction Sequence

…, EJF Bilodeau, AM Beauchemin

文献索引:Rizk, Toni; Bilodeau, Eric J.-F.; Beauchemin, Andre M. Angewandte Chemie - International Edition, 2009 , vol. 48, # 44 p. 8325 - 8327

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被引用次数: 36

摘要

The prevalence and diversity of aromatic nitrogen heterocycles found in natural products and used in medicinal chemistry continues to fuel the development of new methods and strategies for their syntheses.[1] Recently, advances in amination chemistry (eg, CÀH insertions, metal-catalyzed annulations, Buchwald–Hartwig cross-couplings, oxidative aminations, hydroaminations) have enabled routes to diverse aromatic ring systems and ...