Tetrahedron Letters

A synthesis of sulfonamide analogs of platensimycin employing a palladium-mediated carbonylation strategy

J McNulty, JJ Nair, A Capretta

文献索引：McNulty, James; Nair, Jerald J.; Capretta, Alfredo Tetrahedron Letters, 2009 , vol. 50, # 28 p. 4087 - 4091

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被引用次数: 26

摘要

The monodentate ligand 1, 3, 5, 7-tetramethyl-2, 4, 8-trioxa-6-phenyl-6-phospha- adamantane (PA-Ph) is shown to be highly effective in palladium-catalyzed carbonylative cross-coupling. Aryl and vinyl halides were efficiently converted to carboxylic acids, amides and to primary, secondary, and tertiary esters, respectively. Application of the Pd (OAc) 2/PA- Ph (1: 1) catalyst system proved critical in the methoxycarbonylation of a functionalized ...