Tetrahedron Letters

The ultrasound promoted Knoevenagel condensation of aromatic aldehydes

J McNulty, JA Steere, S Wolf

文献索引：McNulty, James; Steere, Jennifer A.; Wolf, Sonja Tetrahedron Letters, 1998 , vol. 39, # 44 p. 8013 - 8016

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被引用次数: 121

摘要

Application of ultrasound has been found to greatly assist the Knoevenagel aldol condensation reaction of activated methylenes with aromatic aldehydes under mild conditions. The outcome of the ultrasound-promoted reaction depends upon the electronic nature of the armoatic aldehyde, the solvent employed and the addition of acids, bases or ammonium salts.