A fluorescently labeled dendronized polymer–enzyme conjugate carrying multiple copies of two different types of active enzymes

…, H Erdogan, AD Schlüter, P Walde

文献索引：Grotzky, Andrea; Nauser, Thomas; Erdogan, Huriye; Schlueter, A. Dieter; Walde, Peter Journal of the American Chemical Society, 2012 , vol. 134, # 28 p. 11392 - 11395

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被引用次数: 41

摘要

A hybrid structure of a synthetic dendronized polymer, two different types of enzymes (superoxide dismutase and horseradish peroxidase), and a fluorescent dye (fluorescein) was synthesized. Thereby, a single polymer chain carried multiple copies of the two enzymes and the fluorescein. The entire attachment chemistry is based on UV/vis- quantifiable bis-aryl hydrazone bond formation that allows direct quantification of bound ...