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Aminopyrazoles with high affinity for the human neuropeptide Y5 receptor

CP Kordik, C Luo, BC Zanoni, SL Dax…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2283 - 2286

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被引用次数: 29

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Replacement of the sulfonamido group with either an amide (48) or a reverse amide (49) resulted in a loss of activity, indicating that the sulfonamide is critical for activity here as it is for some of the other NPY Y5 chemical series, as ...