Molecules

Synthesis and biological evaluation of 3-aryl-quinoxaline-2-carbonitrile 1, 4-di-N-oxide derivatives as hypoxic selective anti-tumor agents

Y Hu, Q Xia, S Shangguan, X Liu, Y Hu, R Sheng

文献索引：Molecules, , vol. 17, # 8 p. 9683 - 9696

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被引用次数: 15

摘要

... affect the anti-tumor activity by changing the electronic and lipophilic properties of the entire molecule. ... tumor activity and hypoxia selectivity because of the disparity in the electronic properties of the resulting molecules. ... for C 17 H 14 N 3 O 2 [M + H] + : 292.1080, found: 292.1083 ...