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Antagonists of the human A2A adenosine receptor. 4. Design, synthesis, and preclinical evaluation of 7-aryltriazolo [4, 5-d] pyrimidines

RJ Gillespie, SJ Bamford, R Botting…

文献索引:Journal of Medicinal Chemistry, , vol. 52, # 1 p. 33 - 47

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被引用次数: 67

摘要

... Journal of Medicinal Chemistry. ... These issues clearly highlight the urgent medical need for an alternative point of therapeutic intervention that can alleviate the symptoms of the disease while additionally offering predictable pharmacokinetics and a reduced incidence of side ...