Regioselective activation of aminothiazole (iminoxyacetic acid) acetic acid: An efficient synthesis of the monobactam aztreonam

J Singh, TW Denzel, R Fox, TP Kissick…

文献索引：Organic Process Research and Development, , vol. 6, # 6 p. 863 - 868

被引用次数: 4

摘要

... Organic Process Research & Development. ... In conclusion we have developed efficient processes for the syntheses of the regioselectively activated aminothiazole ... generated zwitterion 22 provided an alternative efficient synthesis of aztreonam (1). This process was implemented ...

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2-[(2-氨基噻唑-4-基)...

Regioselective activation of aminothiazole (iminoxyacetic ac...

[Singh, Janak; Denzel, Theodor W.; Fox, Rita; Kissick, Thomas P.; Herter, Rolf; Wurdinger, Joseph; Schierling, Peter; Papaioannou, Chris G.; Moniot, Jerome L.; Mueller, Richard H.; Cimarusti, Christopher M. Organic Process Research and Development, 2002 , vol. 6, # 6 p. 863 - 868]