Regioselective activation of aminothiazole (iminoxyacetic acid) acetic acid: An efficient synthesis of the monobactam aztreonam

J Singh, TW Denzel, R Fox, TP Kissick…

Index: Organic Process Research and Development, , vol. 6, # 6 p. 863 - 868

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Citation Number: 4

Abstract

... Organic Process Research & Development. ... In conclusion we have developed efficient processes for the syntheses of the regioselectively activated aminothiazole ... generated zwitterion 22 provided an alternative efficient synthesis of aztreonam (1). This process was implemented ...

Regioselective activation of aminothiazole (iminoxyacetic ac...

[Singh, Janak; Denzel, Theodor W.; Fox, Rita; Kissick, Thomas P.; Herter, Rolf; Wurdinger, Joseph; Schierling, Peter; Papaioannou, Chris G.; Moniot, Jerome L.; Mueller, Richard H.; Cimarusti, Christopher M. Organic Process Research and Development, 2002 , vol. 6, # 6 p. 863 - 868]