Synthesis of novel N-1 (allyloxymethyl) analogues of 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine) with improved activity against HIV-1 and its …

NR El-Brollosy, PT Jørgensen, B Dahan…

文献索引：Nazaretyan; Torosyan; Babayan Journal of applied chemistry of the USSR, 1985 , vol. 58, # 11 pt 2 p. 2396 - 2400

被引用次数: 58

摘要

... Journal of Medicinal Chemistry. ... J. Med. Chem. ... Chemistry. The synthesis of the newly designed products was straightforward and is described in Scheme 1. The acetals 6 were prepared according to the method of Nazaretyan et al. ...

~67%

~59%

~85%

~46%

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