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Tetrahedron

Fluoride ion-catalyzed conjugate addition for easy synthesis of 3-sulfanylpropionic acid from thiol and α, β-unsaturated carboxylic acid

S Gao, C Tseng, CH Tsai, CF Yao

文献索引:Gao, Shijay; Tseng, Chi; Tsai, Cheng Hsuan; Yao, Ching-Fa Tetrahedron, 2008 , vol. 64, # 8 p. 1955 - 1961

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被引用次数: 15

摘要

The conjugate addition is one of the efficient methods in organic synthesis for the formation of carbon–carbon, carbon–sulfur, and carbon–nitrogen bonds. 1 Among various nucleophilic additions, the conjugate addition of thiols to various unsaturated systems to form a carbon–sulfur bond is of much importance, as it comprises a key reaction in the biosynthesis and the synthesis of several biologically active compounds. 2, 2a, 2b, 2c, 2d, 2e and 2f A number of ...