General anesthetics. 2. Halogenated methyl isopropyl ethers

L Speers, AJ Szur, RC Terrell, J Treadwell…

文献索引：Speers,L. et al. Journal of Medicinal Chemistry, 1971 , vol. 14, p. 593 - 595

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被引用次数: 19

摘要

The first study of the anesthetic properties of fluorinated hydrocarbons was reported by Robbins' in 1946. Since that time many fluorinated compounds, both hydrocarbons and ethers, have been found to have anesthetic properties in laboratory animals and several have progressed to clinical trials in human^.^^^ Fluoroxene (CF3CH20CH= CH2), halothane (CF3CHC1Br), and methoxyflurane (CH3OCF2CHC12) are presently in clinical ...