General anesthetics. 2. Halogenated methyl isopropyl ethers

L Speers, AJ Szur, RC Terrell, J Treadwell…

Index: Speers,L. et al. Journal of Medicinal Chemistry, 1971 , vol. 14, p. 593 - 595

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Citation Number: 19

Abstract

The first study of the anesthetic properties of fluorinated hydrocarbons was reported by Robbins' in 1946. Since that time many fluorinated compounds, both hydrocarbons and ethers, have been found to have anesthetic properties in laboratory animals and several have progressed to clinical trials in human^.^^^ Fluoroxene (CF3CH20CH= CH2), halothane (CF3CHC1Br), and methoxyflurane (CH3OCF2CHC12) are presently in clinical ...