Tetrahedron

Synthesis and photophysical characterization of 1-and 4-(purinyl) triazoles

IN Redwan, D Bliman, M Tokugawa, C Lawson…

文献索引：Redwan, Itedale Namro; Bliman, David; Tokugawa, Munefumi; Lawson, Christopher; Grotli, Morten Tetrahedron, 2013 , vol. 69, # 42 p. 8857 - 8864

全文：HTML全文

被引用次数: 6

摘要

Abstract Fluorescent adenine mimetics are useful tools for studying DNA, RNA and enzyme functions. Herein we describe the synthesis of eight 1-(purinyl) triazoles and two 4-(purinyl) triazoles utilizing the 1, 4-regioselective copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction as the key step. The fluorescence properties of five of the synthesized 1- (purinyl) triazoles are also presented. The five measured compounds displayed low ...