Abstract Fluorescent adenine mimetics are useful tools for studying DNA, RNA and enzyme functions. Herein we describe the synthesis of eight 1-(purinyl) triazoles and two 4-(purinyl) triazoles utilizing the 1, 4-regioselective copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction as the key step. The fluorescence properties of five of the synthesized 1- (purinyl) triazoles are also presented. The five measured compounds displayed low ...
