Enantioselective hydrogenation of β??keto esters using chiral diphosphine??ruthenium complexes: Optimization for academic and industrial purposes and synthetic …

V Ratovelomanana??Vidal, C Girard…

文献索引：Ratovelomanana-Vidal; Girard; Touati; Tranchier; Ben Hassine; Genet Advanced Synthesis and Catalysis, 2003 , vol. 345, # 1-2 p. 261 - 274

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被引用次数: 93

摘要

Abstract Enantioselective hydrogenation using chiral complexes between atropisomeric diphosphines and ruthenium is a powerful tool for producing chiral compounds. Using a simple and straightforward in situ catalyst preparation, the conditions were optimized using molecular hydrogen for both academic and industrial purposes. This led to the best conditions and the lowest catalytic ratio required for the pressure used. Hydrogenation of ...