Efficient,“tin-free” radical cyclization to aromatic systems. Synthesis of 5, 6, 8, 9, 10, 11-hexahydroindolo [2, 1-a] isoquinolines

…, R Cruz-Almanza, JM Muchowski…

文献索引：Menes-Arzate, Martha; Martinez, Roberto; Cruz-Almanza, Raymundo; Muchowski, Joseph M.; Osornio, Yazmin M.; Miranda, Luis D. Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 4001 - 4004

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被引用次数: 44

摘要

Efficient radical cyclization of alkyl iodides to various aromatic systems including pyrrole, indole, isoquinolone, pyridone, and benzene, mediated by dicumyl peroxide, is described. The methodology was used to provide access to 5, 6, 8, 9, 10, 11-hexahydroindolo [2, 1-a] isoquinoline derivatives.