Polar effects in free-radical reactions. Homolytic heteroaromatic substitutions by alkyl bromides

F Minisci, F Fontana, G Pianese…

文献索引：Minisci, Francesco; Fontana, Francesca; Pianese, Guiseppe; Yan, Yong Ming Journal of Organic Chemistry, 1993 , vol. 58, # 16 p. 4207 - 4211

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被引用次数: 40

摘要

Results Tributyltin hydride. BuaSnH reacts in refluxing acetonitrile with alkyl bromides and stoichiometric amounts of azobisisobutyronitrile (AIBN) in the presence of protonated lepidine to give the selective substitution in position 2 (eq 5). The BusSnH solution was dropped in

~88%

~93%

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