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Efficient Iodine-catalyzed Synthesis of 3-Aryl 4 (3 H)-quinazolinones

M Wang, ZG Song, TT Zhang

文献索引:Wang, Min; Song, Zhi-Guo; Zhang, Ting-Ting Organic Preparations and Procedures International, 2010 , vol. 42, # 2 p. 169 - 173

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被引用次数: 5

摘要

Compounds with a 4-quinazolinone motif have displayed a variety of interesting pharmacological properties such as antimalarial, antitumor, anticonvulsant, antiinflammatory, fungicidal, antimicrobial and calcilytic activities. 1–7 An examination of the literature indicates that 4-quinazolinones substituted at the 3-position are attracting the attention of chemists because they appear to have important sedative, hypnotic and ...