Tetrahedron Letters

A remarkable catalytic effect of Cu (II) species for conjugate addition of grignard reagents to α, β-unsaturated esters

H Sakata, Y Aoki, I Kuwajima

文献索引：Sakata, Hiroshi; Aoki, Youji; Kuwajima, Isao Tetrahedron Letters, 1990 , vol. 31, # 8 p. 1161 - 1164

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被引用次数: 28

摘要

Hiroshi Sakata, Youji Aoki, and Isao Kuwajima* Department of Chemistry, Tokyo Institute of Technolo~, Megum, Tokyo 152, Ja~m ... Abstract: In the presence of Me@i-Cl, Cu(II) are not reduced by Grignard reagents but exhibit remarkable catalytic activity for their conjugate addition to a&unsaturate4l esters. ... Since Kharasch's finding,l) Cu(1) salts have been often employed as efficient catalysts for conjugate addition of Grignard reagents,2) but efficacy of Cu(I1) ...