Chemoselective synthesis of quinoline N??oxides from 3??(2??nitrophenyl)??3??hydroxypropanones

K Okuma, J Seto, N Nagahora…

文献索引：Okuma, Kentaro; Seto, Jun-Ichi; Nagahora, Noriyoshi; Shioji, Kosei Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 6 p. 1372 - 1378

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被引用次数: 7

摘要

Quinoline ring framework can be found in many synthetic and natural compounds of biological importance. Especially, quinoline N-oxides (1) are important compounds because of their biological activity [1]. The quinoline N-oxide core unit has been found in drugs exerting microsomal Na, K-ATPase [2], antiviral [3], or antimalarian activities [4]. The synthetic method of quinoline N-oxide mainly devoted to the oxidation of the ...