Synthetic Study of Colchicine

M Kato, F Kido, MD Wu, A Yoshikoshi

文献索引：Kato; Kido; Wu; Yoshikoshi Bulletin of the Chemical Society of Japan, 1974 , vol. 47, # 4 p. 1516 - 1521

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被引用次数: 36

摘要

An efficient route based upon solvolytic fragmentation of a cyclopentadiene-dichloroketene adduct 4c has been investigated for the synthesis of trimethoxyphenylpropyltropolone 2b, a synthetic intermediate of colchicine 1a. Attempted synthesis of the corresponding unsaturated tropolones 8a and 10 is also discussed.