Zinc chloride promoted efficient and facile BOC protection of amines

M Arifuddin, N Lakshmikant, N Rajasekar…

文献索引：Arifuddin, M.; Lakshmikant, N.; Rajasekar, N.; Shinde, D. B. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2012 , vol. 51, # 8 p. 1168 - 1172,5

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被引用次数: 5

摘要

Abstract: Amines are efficiently protected as their BOC derivatives under mild reaction conditions when reacted with BOC anhydride in presence of ZnCl 2. The present method is applicable to a variety of amines including aliphatic, aromatic as well as heteroaromatic amines. T his protocol appears to be competitive and in some cases superior to previously reported procedures that work under basic conditions.