Abstract To obtain 2-benzimidazolyl acrylate 2, a new efficient synthesis of 2- benzimidazoleacetate, involving esterification of 2-benzimidazole acetic acid at low temperature as the crucial step, was developed. The generality and efficiency of the process was illustrated by the high-yield synthesis of methyl, ethyl, i-propyl, and n-butyl 2- benzimidazoleacetate. The Knoevenagel reaction of 2-benzimidazoleacetate with ...
