Conformational studies by dynamic NMR—2511Part 24. L. Lunazzi, M. Guerra, D. Macciantelli and G. Cerioni, J. Chem. Soc. Perkin II, 1982 in press.: Stereomutations …
The trend toward steric acceleration for N-inversion and steric deceleration for CN rotation has been verified in an homogeneous series of tertiary isopropylamines. Unambiguous evidence has been obtained that in a crowded amine (3-pentyl diisopropylamine) the barrier to rotation becomes higher than that to inversion. It has also been shown that this amine adopts an eclipsed, rather than a staggered dynamic conformation.
