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Amino-acids and peptides. Part XXVI. The use of 1-piperidyl esters in peptide synthesis: further studies

JH Jones, B Liberek, GT Young

文献索引:Jones,J.H. et al. Journal of the Chemical Society [Section] C: Organic, 1967 , p. 2371 - 2374

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被引用次数: 7

摘要

Further examples of the use of 1-piperidyl esters for the synthesis of protected dipeptides have given good yields of pure product except when two valine residues were involved (in which case the reaction of the analogous p-nitrophenyl ester was also very slow), or when one residue was α-aminoisobutyric acid. The reactions of benzyloxy-carbonylamino-acid 1- piperidyl esters with the methyl esters of L-leucyl-L-leucylglycine, L-phenylalanyl-L- ...