Chemical Communications

Three-component access to pyrroles promoted by the CAN–silver nitrate system under high-speed vibration milling conditions: a generalization of the Hantzsch …

V Estevez, M Villacampa, JC Menéndez

文献索引：Estevez, Veronica; Villacampa, Mercedes; Menendez, J. Carlos Chemical Communications, 2013 , vol. 49, # 6 p. 591 - 593

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被引用次数: 53

摘要

A sequential multicomponent process involving the high-speed vibration milling of ketones with N-iodosuccinimide and p-toluenesulfonic acid, followed by addition of a mixture of primary amines, β-dicarbonyl compounds, cerium (IV) ammonium nitrate and silver nitrate afforded polysubstituted, functionalized pyrroles. This one-pot, solid-state process can be considered as the coupling of an α-iodoketone preparation with a general version of the ...