Nickel-catalyzed Suzuki–Miyaura reaction of aryl fluorides

…, T Xu, T Shimasaki, N Chatani

文献索引：Shiota, Hirotaka; Ano, Yusuke; Aihara, Yoshinori; Fukumoto, Yoshiya; Chatani, Naoto Journal of the American Chemical Society, 2011 , vol. 133, # 38 p. 14952 - 14955

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被引用次数: 101

摘要

Two protocols for the nickel-catalyzed cross-coupling of aryl fluorides with aryl boronic esters have been developed. The first employs metal fluoride cocatalysts, such as ZrF4 and TiF4, which enable Suzuki–Miyaura reactions of aryl fluorides bearing electron-withdrawing (ketones, esters, and CF3), aryl and alkenyl groups as well as those comprising fused aromatic rings, such as fluoronaphthalenes and fluoroquinolines. The second protocol ...