Tricyclic purine analogs derived from 2-amino-6-chloropurine and 2, 6-diaminopurine and their methylated quaternary salts

K Hořejší, R Pohl, A Holý

文献索引：Horejsi, Katerina; Pohl, Radek; Holy, Antonin Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 1 p. 77 - 90

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被引用次数: 2

摘要

Abstract A novel series of tricyclic, etheno-bridged purine analogs was sythesized from 2- amino-6-(substituted amino)-9-methylpurines by cyclization with chloroacetaldehyde, with particular focus on the regioselectivity of the cyclization reaction and fluorescence properties. The analogs as well as the starting purines were alkylated with iodomethane, affording a new class of quaternary salts with potential biological activity. Neither ...