Abstract Acetamide/SO 2 Cl 2 reagent has been developed for effective Friedel–Craft's acylation of aromatic compounds. Acylation of aromatic compounds with acetamide/SO 2 Cl 2 was much more effective and faster than analogous (acetamide/SOCl 2) and (acetamide/POCl 3) reagents even under conventional conditions. However, microwave and ultrasonic assisted reactions afforded high yields of products in very short reaction times ( ...