Acetamide/SO 2 Cl 2 as an efficient reagent for Friedel–Craft's acylation of aromatic compounds under ultrasonic and microwave conditions

…, KC Rajanna, P Venkanna, M Venkateswarlu

Index: Satish Kumar, Mukka; Chinna Rajanna, Kamatala; Venkanna, Purugula; Venkateswarlu, Marri Tetrahedron Letters, 2014 , vol. 55, # 10 p. 1756 - 1759

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Citation Number: 3

Abstract

Abstract Acetamide/SO 2 Cl 2 reagent has been developed for effective Friedel–Craft's acylation of aromatic compounds. Acylation of aromatic compounds with acetamide/SO 2 Cl 2 was much more effective and faster than analogous (acetamide/SOCl 2) and (acetamide/POCl 3) reagents even under conventional conditions. However, microwave and ultrasonic assisted reactions afforded high yields of products in very short reaction times ( ...