Chemical Communications

A highly efficient oxidative condensation reaction for selective protein conjugation

A Ji, W Ren, H Ai

文献索引：Ji, Ao; Ren, Wei; Ai, Hui-Wang Chemical Communications, 2014 , vol. 50, # 56 p. 7469 - 7472

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被引用次数: 6

摘要

We hereby report a mild and efficient coupling reaction between alkyl aldehydes and aryl diamines. In the presence of a Cu2+ or a Zn2+ ion, oxygen (O2) in air is able to promote the oxidative condensation of the two readily preparable functional groups, forming stable