Chemical Communications

A highly efficient oxidative condensation reaction for selective protein conjugation

A Ji, W Ren, H Ai

Index: Ji, Ao; Ren, Wei; Ai, Hui-Wang Chemical Communications, 2014 , vol. 50, # 56 p. 7469 - 7472

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Citation Number: 6

Abstract

We hereby report a mild and efficient coupling reaction between alkyl aldehydes and aryl diamines. In the presence of a Cu2+ or a Zn2+ ion, oxygen (O2) in air is able to promote the oxidative condensation of the two readily preparable functional groups, forming stable

~82%

Design, synthesis, and docking studies of novel benzimidazol...

[Mizuno, Cassia S.; Chittiboyina, Amar G.; Shah, Falgun H.; Patny, Akshay; Kurtz, Theodore W.; Pershadsingh, Harrihar A.; Speth, Robert C.; Karamyan, Vardan T.; Carvalho, Paulo B.; Avery, Mitchell A. Journal of Medicinal Chemistry, 2010 , vol. 53, # 3 p. 1076 - 1085]