Tetrahedron

Regioselectivity in the C-acylation of 2 (3H)-benzoxazolones

H Aichaoui, JH Poupaert, D Lesieur, JP Hénichart

文献索引：Aichaoui, Hocine; Poupaert, Jacques H.; Lesieur, Daniel; Henichart, Jean-Pierre Tetrahedron, 1991 , vol. 47, # 33 p. 6649 - 6654

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被引用次数: 54

摘要

Unequivocal synthetic routes towards 5-and 6-acyl-2 (3H)-benzoxazolones are described. Comparison of the physicochemical properties of the compounds obtained by direct acylation under various Friedel-Crafts reaction conditions always leads to the conclusion that 6-acyl derivatives are the only isolated products. This observation contradicts previously published results.