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The addition of hydrogen halides to the carbonyl group to give gem-halogenohydrins

MD McManus, JBB Skinner…

文献索引:Mcmanus, Michael D.; Skinner, James B.B.; Peter Hughes Journal of Chemical Research, 2011 , vol. 35, # 6 p. 361 - 363

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摘要

By conductivity measurements, it has been shown that HCl, HBr and HI undergo addition to propanone and propanal to give gem-halogenohydrins. Chlorohydrins have been detected when HCl combined with aldehydes that do not undergo keto-enol tautomerism and 1, 2, 2, 2-tetrachlorethanol has been identified when HCl combines with trichloroethanal (chloral). The formation of gem-chlorohydrins has been reported in the enzymic degradation of ...