Synthesis and antitumor properties of pyrrolophenanthridines

…, EP Baberkina, ME Samoilova, RN Akhvlediani…

文献索引：Buyanov, V. N.; Baberkina, E. P.; Samoilova, M. E.; Akhvlediani, R. N.; Frolova, E. P.; et al. Pharmaceutical Chemistry Journal, 1994 , vol. 28, # 1 p. 11 - 16 Khimiko-Farmatsevticheskii Zhurnal, 1994 , vol. 28, # 1 p. 10 - 14

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被引用次数: 3

摘要

In order to obtain the hydrazones (V, VII, IX), the corresponding aminophenanthridines were diazotized and the diazonium salts formed were reduced by tin chloride in hydrochloric acid. The hydrazines obtained were condensed (without preliminary separation) with pyrotartaric acid. In this case, the yields of phenanthridyl hydrazones of pyrotartaric acid V, VII, IX were- 75%.