Tetrahedron

Arylzinc species by microwave assisted Grignard formation–transmetallation sequence: application in the Negishi coupling

I Mutule, E Suna

文献索引：Mutule, Ilga; Suna, Edgars Tetrahedron, 2005 , vol. 61, # 47 p. 11168 - 11176

全文：HTML全文

被引用次数: 39

摘要

Arylmagnesium species can be efficiently generated from magnesium turnings and aryl chlorides or aryl bromides under dielectric heating conditions. Subsequent microwave assisted transmetallation using ZnCl2–TMEDA afforded the corresponding arylzinc reagents. A sequential microwave assisted arylmagnesium formation–transmetallation– Negishi coupling protocol suitable for automated multiple parallel synthesis has been ...