This work evaluates the chemical stability of the composition YIn0.95Mn0.05O3, through exposure of the material to different acidic, basic and neutral media and the incorporation into an aqueous base of white paint. A high structural stability is evidenced for the different used media except for the acidic solvents, which causes a strong degradation of the optical properties of the material. The latter is due to the presence of a MnO2-type phase, possibly amorphous and/or in a low concentration, evidenced at the microscopic level and associated with an oxidation of Mn3+ cation at the surface of the material. Nevertheless, the integration of the pigment into a water-based paint presents suitable properties to the chemical attack of alkali and acid solvents, favouring the future application of the material in the industrial sector of paints and coatings.