The effects of 4′-alkyl substituents on the mutagenic activity of 4-amino-and 4-nitrostilbenes in Salmonella typhimurium

B Ludolph, M Klein, L Erdinger, G Boche

文献索引：Ludolph, Bjoern; Klein, Markus; Erdinger, Lothar; Boche, Gernot Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2001 , vol. 491, # 1-2 p. 195 - 209

全文：HTML全文

被引用次数: 8

摘要

Six derivatives of trans-4-aminostilbene bearing different alkyl groups in the 4′-position and six of the corresponding nitro compounds were synthesized and tested for their mutagenic potency in Salmonellatyphimurium strains TA98 and TA100. Regarding the test series in presence of S9-mix, maximum activity was observed for those trans-4- aminostilbenes and trans-4-nitrostilbenes bearing small alkyl substituents like methyl and ...