Regioselective N??Alkylation of 2??Aminoimidazoles with Alcohols to 2??(N??Alkylamino) imidazoles Catalyzed by the [Cp* IrCl2] 2/K2CO3 System

…, Q Kang, H Shan, L Chen, J Xie

文献索引：Li, Feng; Kang, Qikai; Shan, Haixia; Chen, Lin; Xie, Jianjiang European Journal of Organic Chemistry, 2012 , # 26 p. 5085 - 5092

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被引用次数: 6

摘要

Abstract The direct N-alkylation of 2-aminoimidazoles to give the corresponding 2-(N- alkylamino) imidazoles was accomplished using alcohols as alkylating agents in the presence of a [Cp* IrCl 2] 2/K 2 CO 3 system. The iridium-catalyzed regioselective reaction is simple, efficient, general, and environmentally benign.