Direct oxidative Heck cyclizations: intramolecular Fujiwara–Moritani arylations for the synthesis of functionalized benzofurans and dihydrobenzofurans

H Zhang, EM Ferreira, BM Stoltz

文献索引：Zhang, Haiming; Ferreira, Eric M.; Stoltz, Brian M. Angewandte Chemie - International Edition, 2004 , vol. 43, # 45 p. 6144 - 6148

全文：HTML全文

被引用次数: 181

摘要

Over the past two and a half decades, the intramolecular Heck reaction has proven to be an integral process for the formation of CÀC linkages in the synthesis of complex molecules.[1] While the reaction provides desirable products by the coupling of an aryl or vinyl halide with an olefin by extrusion of the hydrohalic acid, the overall process involves two discrete functionalization events: 1) halogenation of an aryl or vinyl precursor and 2) palladium (0)- ...