Palladium-catalyzed intramolecular CO bond formation

…, KE Torraca, SL Buchwald

文献索引：Kuwabe; Torraca; Buchwald Journal of the American Chemical Society, 2001 , vol. 123, # 49 p. 12202 - 12206

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被引用次数: 256

摘要

A number of oxygen heterocycles were synthesized using the palladium-catalyzed intramolecular etherification of aryl halides by employing di-tert-butylphosphinobiaryl ligands. The reaction proceeds under mild conditions using weak bases such as Cs2CO3 or K3PO4. A variety of functional groups are tolerated in the reaction, and enantioenriched alcohols can be coupled without erosion of optical purity. The mildness of the reaction ...