Phosphoramidite Ligands in Iridium??Catalyzed Allylic Substitution

D Polet, A Alexakis, K Tissot??Croset…

文献索引：Polet, Damien; Alexakis, Alexandre; Tissot-Croset, Karine; Corminboeuf, Clemence; Ditrich, Klaus Chemistry - A European Journal, 2006 , vol. 12, # 13 p. 3596 - 3609

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被引用次数: 172

摘要

Abstract A new phosphoramidite ligand was used in the iridium-catalyzed allylic substitution reaction. This permitted high regio-and enantioselectivities on a wide variety of substrates and nucleophiles. Because of the stereospecificity of the reaction obtained by using branched substrates, a kinetic resolution reaction was attempted. The origin of the impressive efficiency of this ligand in terms of kinetics was explored in detail, as was the ...