Synlett

A convenient procedure for parallel ester hydrolysis

MO Anderson, J Moser, J Sherrill, RK Guy

文献索引：Anderson, Marc O.; Moser, Jamie; Sherrill, John; Guy, R. Kiplin Synlett, 2004 , # 13 p. 2391 - 2393

被引用次数: 12

摘要

Abstract The treatment of alkyl esters with barium hydroxide octahydrate in methanol followed by protonation with anhydrous hydrogen chloride affords carboxylic acids. The procedure does not require aqueous workup and is particularly suitable for parallel synthesis applications.

455-14-1

4-氨基三氟甲苯

~99%

~84%

~99%

~85%

Parallel synthesis of 9-aminoacridines and their evaluation ...

[Anderson, Marc O.; Sherrill, John; Madrid, Peter B.; Liou, Ally P.; Weisman, Jennifer L.; DeRisi, Joseph L.; Guy, R. Kiplin Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 2 p. 334 - 343]