Facile Synthesis of Bioactive 4H-[1, 4]-Benzothiazines Under Solvent Free Conditions

…, S Chomal, S Choudhary

文献索引：Kalwania; Chomal; Choudhary, Savita Asian Journal of Chemistry, 2011 , vol. 23, # 11 p. 5133 - 5136

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被引用次数: 1

摘要

Abstract An efficient method for synthesis of 4H-[1, 4]-benzothiazines under solvent free conditions has been developed. The oxidative condensation of 2-aminobenzenethiols with β- diketones/β-ketoesters in presence of catalytic amount of hydrazine hydrate yields the 4H-[1, 4]-benzothiazines. The reaction is accelerated by microwave irradiation under solvent free conditions in presence of an energy transfer agent DMF to get the product in high yield. ...