Tetrahedron

Facile and stereoselective synthesis of (E)-vinyl bromides by microwave-induced reaction of 1, 1-dibromoalkenes using a diethyl phosphonate/EtONa/EtOH system

C Kuang, H Senboku, M Tokuda

文献索引：Kuang, Chunxiang; Senboku, Hisanori; Tokuda, Masao Tetrahedron, 2002 , vol. 58, # 8 p. 1491 - 1496

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被引用次数: 55

摘要

(E)-Vinyl bromides were readily prepared from 1, 1-dibromoalkenes by microwave irradiation within 1min using a diethyl phosphonate/EtONa/EtOH system. This method utilizes cheap and environmentally friendly reagents, requires only a short reaction time, and gives (E)-vinyl bromides in high stereoselectivities and high yields.