2, 3, 9-and 2, 3, 11-Trisubstituted tetrahydroprotoberberines as D 2 dopaminergic ligands

J Párraga, N Cabedo, S Andujar, L Piqueras…

文献索引：Parraga, Javier; Cabedo, Nuria; Andujar, Sebastian; Piqueras, Laura; Moreno, Laura; Galan, Abraham; Angelina, Emilio; Enriz, Ricardo D.; Ivorra, Maria Dolores; Sanz, Maria Jesus; Cortes, Diego European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 150 - 166

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被引用次数: 12

摘要

Abstract Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and neurological disorders. Nowadays, there is an enormous interest in the development of new dopamine receptors (DR) acting drugs as potential new targets for the treatment of schizophrenia or Parkinson's disease. Previous studies have revealed that isoquinoline compounds such as tetrahydroisoquinolines (THIQs) and ...