Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1, 2, 3-triazoles

…, SMA Hussaini, S Faazil, Y Poornachandra…

文献索引：Kamal, Ahmed; Hussaini, Syed Mohammed Ali; Faazil, Shaikh; Poornachandra; Narender Reddy; Kumar, C. Ganesh; Rajput, Vikrant Singh; Rani, Chitra; Sharma, Rashmi; Khan, Inshad Ali; Jagadeesh Babu Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 24 p. 6842 - 6846

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被引用次数: 13

摘要

Abstract A series of 5-nitrofuran–triazole conjugates were synthesized and evaluated for their antimicrobial activity against both Gram-positive and Gram-negative bacterial strains. All the compounds exhibited promising inhibition towards Gram-positive pathogenic strains, while mild inhibitory effects were observed towards Gram-negative bacterial strains. Some of the compounds 8a, 8b, 8e, 8f, 8h are most active among the series exhibiting MIC value of ...